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V2, RHUFAB
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DeCS
Descriptor
English
:
Ranibizumab
Descriptor
Spanish
:
Ranibizumab
Descriptor
Portuguese
:
Ranibizumab
Synonyms
English
:
Lucentis
RhuFab V2
V2, RhuFab
Tree Number:
D12.776.124.486.485.114.224.060.868
D12.776.124.790.651.114.224.060.868
D12.776.377.715.548.114.224.200.868
Definition
English
:
A recombinant humanized monoclonal antibody fragment that binds VEGF-A to prevent its binding to VEGFR-1 and VEGFR-2 receptors. This activity reduces vessel
permeability
and angiogenesis in the treatment of neovascular age-related
MACULAR DEGENERATION.
Pharmacological Action:
Angiogenesis Inhibitors
See Related
English
:
Vascular Endothelial Growth Factor A
History Note
English
:
2016 (2005)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55979
Unique Identifier:
D000069579
Occurrence in VHL
:
Similar:
DeCS